29 May Subvisible particle formation under mechanical and interfacial stress: A case study using bovine serum albumin as a model for biotherapeutic proteins
Improving Our Understanding of the Mechanisms Behind Protein Aggregation in Biologics The stability of protein treatments, such as enzyme replacements and monoclonal antibodies, is an ongoing challenge in modern medicine. Using the model protein BSA, we methodically analyze the role of different mechanical and interfacial stresses in...