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Interface motion and hydrodynamic shear of the liquid slosh during the insertion of syringes upon autoinjector (AI) activation may damage the protein drug molecules. We experimentally investigate the interfacial motion and hydrodynamic shear due to the acceleration and deceleration of syringes. No study to date...

With advancements in biotechnology, the production of highly concentrated antibody formulations for subcutaneous injections is becoming common in the biopharmaceutical industry. Measurement of transport and more importantly diffusion of proteins in tissues is essential in drug development. There is evidence suggesting that the assumption of the...