Interface motion and hydrodynamic shear of the liquid slosh during the insertion of syringes upon autoinjector (AI) activation may damage the protein drug molecules. We experimentally investigate the interfacial motion and hydrodynamic shear due to the acceleration and deceleration of syringes. No study to date...
Pharmaceutical industry focuses on developing prefilled syringe and autoinjector (AI) products by expanding features and capabilities. However, most of them might not be aware of an undesired phenomenon that may occur during drug solution injection called cavitation collapse. Cavitation is a phenomenon in which rapid...
Autoinjectors are drug delivery medical devices for self-administered injection of biopharmaceuticals. Even though the working principle of single-spring-actuated autoinjectors is similar, differences in device design can affect the functionality and performance. From an engineering point of view, this study investigates the performance differences of two...