Biomedical and Biological Flows
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04 Jan

Posted at 16:30h in Biomedical and Biological Flows, Computation Fluid Dynamics, Fluid Dynamics, Measurement and Data Science by
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This study introduces a novel wall shear stress (WSS) estimation method for 4D flow MRI. The method improves the WSS accuracy by using the reconstructed pressure gradient and the flow-physics constraints to correct velocity gradient estimation. The method was tested on synthetic 4D flow data...

19 Dec

Posted at 00:03h in Biomedical and Biological Flows, Biomedical Device, Fluid Dynamics by
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Interface motion and hydrodynamic shear of the liquid slosh during the insertion of syringes upon autoinjector (AI) activation may damage the protein drug molecules. We experimentally investigate the interfacial motion and hydrodynamic shear due to the acceleration and deceleration of syringes. No study to date...

30 May

Posted at 01:03h in Biomedical and Biological Flows, Measurement and Data Science by
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With advancements in biotechnology, the production of highly concentrated antibody formulations for subcutaneous injections is becoming common in the biopharmaceutical industry. Measurement of transport and more importantly diffusion of proteins in tissues is essential in drug development. There is evidence suggesting that the assumption of the...

27 Jan

Posted at 16:41h in Biomedical and Biological Flows, Fluid Dynamics, Measurement and Data Science by
3 Likes

4D flow magnetic resonance imaging (MRI) allows for the in vivo acquisition of time-resolved three-dimensional (3D) blood flow, enabling the evaluation of hemodynamic quantities for cerebral aneurysms (CAs). However, the accuracy of flow-derived hemodynamic quantities such as pressure and wall shear stress (WSS) is affected...

22 Sep

Posted at 11:25h in Biomedical and Biological Flows, Fluid Dynamics by
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Silicone Sylgard 184 (PDMS) is commonly used when manufacturing geometries for bioflow studies due to its optical transparency and compliant nature. However, for use with particle image velocimetry (PIV), a suitable blood analog working fluid is needed which both matches the physical properties of blood...

14 Sep

Posted at 15:57h in Biomedical and Biological Flows, Fluid Dynamics, Measurement and Data Science by
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4D flow magnetic resonance imaging (MRI) allows for in vivo acquisition of time-resolved three-dimensional (3D) blood flow, thus enabling quantitative analysis of volumetric, time-varying hemodynamic quantities such as flow rates, wall shear stress (WSS), pressure difference, etc. 4D flow MRI is based on the phase...

25 May

Posted at 13:56h in Biomedical and Biological Flows, Echocardiography by
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B-mode Speckle Tracking Echocardiography (STE) estimates the change in myocardial tissue length during a heartbeat. Commercial STE software use block-matching to track local speckle patterns and advect hand-drawn boundaries through these tracks to estimate length change. Strain is gaining adoption as a clinical metric for...

25 May

Posted at 08:18h in Biomedical and Biological Flows, Echocardiography, Measurement and Data Science by
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Echocardiogram Particle Image Velocimetry (echoPIV) is an emerging method for cardiac flow visualization. EchoPIV tracks acoustic-opaque bubbles introduced into the blood stream using block-matching methods. Despite increased interest, echoPIV is not routinely performed, as contrast enhancement is not clinically indicated unless initial image quality is...

30 Apr

Posted at 15:15h in Biomedical and Biological Flows, Computation Fluid Dynamics, Echocardiography by
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Visualization and quantitation of multi-directional cardiovascular flow without the need for sedation or contrast is desirable across all practices of cardiology. Intraventricular flow mapping (iVFM) is one such method for multi-direction visualization. iVFM estimates the transverse flow from color Doppler ultrasound using the continuity equation....